Ritu Pandey, PhD

Associate Research Professor
Associate Director, Translational Clinical Bioinformatics
Coordinator, Biomedical Informatics
Graduate - Graduate Degree Seeking - Healthcare Management
 
Education: 
  • College of Agriculture and Life Sciences, University of Arizona,(Post-Doctoral Res. Associate - Bioinformatics)
  • School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, (Ph.D.)
  • School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, (M.Sc. Life Sciences Inter-disciplinary program)
  • BHU, Varanasi, India, (B.Sc.,Honors)
Major Areas of Research Interest: 
We do data driven cancer research. Our interest is to investigate underlying molecular events (changes in DNA, RNA and proteome) that occur in cancer cells. We study tumor cohorts by integrated computational analysis of clinical and molecular data from multi-omics projects. Our goal is to translate the data sets into insights that advance understanding of biomarkers/therapeutic targets and response to treatment.
 
Selected Publications: 
Larson KR, Kannaiyan R, Pandey R, Chen Y#, Babiker H, Mahadevan D (2020). A Comparative
Analysis of Tumor and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients annotated by 3 
Core Cellular Processes. Cancers (Basel). Mar 16;12(3). pii: E701. doi: 10.3390/
cancers12030701.
 
Singh N, Padi SKR, Bearss JJ, Pandey R, Okumura K, Beltran H, Song JH, Kraft, AS, Olive V
(2020) PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell 
gene transcription and modulate tumor growth. Journal of Molecular Oncology 2020 Mar 7. doi: 
10.1002/1878-0261.12662. [Epub ahead of print] PMID: 32146726
 
Pandey R*, Zhou M#, Islam S, Chen B, Barker N, Langlais P, Srivastava A, Cooke LS, Weterings E, 
Mahadevan D. (2019) Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic 
Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target.
Scientific Reports Rep. 2019 Dec 4;9(1):18347. PMID: 31797958
 
Chen H, Sells E, Pandey R, Abril E, Hsu C, Krouse R, Nagle RB, Pampalakis G, Sotiropoulou G, 
Ignatenko NA. (2019) Kallikrein 6 protease advances colon tumorigenesis via induction of the high 
mobility group A2 protein. Oncotarget Oct 22; 10(58): 6062-6078. PMID:31692974
 
Song JH, Kang H, Luevano LA, Gokhale V, Wu K, Pandey R, Chow SHH, Hurley LH, Kraft AS (2019). 
Small-molecule targeting hairpin loop of hTERT promoter G-quadruplex induces cancer cell death. 
Cell Chemical Biology May 13. pii: S2451-9456(19)30140-0. doi: 10.1016/j.chembiol.2019.04.009. 
PMID:31155510
 
Pandey R*, Woo H, Varghese F#, Zhou M#, Chambers SK. (2019) Circulating miRNA profiling of women at 
high risk for ovarian cancer. Translational Oncology 8;12(5):714-725. PMID:30856556

Padi SKR, Luevano LA, An N, Pandey R, Singh N, Song J, Aster J, Yu X, Mehrotra S and Kraft AS 
(2017) Targeting the PIM Protein Kinases for the Treatment of a T-cell Acute Lymphoblastic Leukemia 
Subset Oncotarget- 8(18): 30199-30216 PMID:28415816.

Sells E, Pandey R, Chen H, Skovan BA, Cui H and Ignatenko NA (2017). Specific microRNA- mRNA 
regulatory network of colon cancer invasion mediated by tissue kallikrein-related peptidase6 
Neoplasia 19(5):396-411. PMID: 28431272

* Indicates Corresponding author is R. Pandey
# Indicates Mentored graduate Students as coauthors
 
Sponsored Research Through MSRP: 
Emily Wusterbarth, (MSRP 2020): "Analysis of The Cancer Genome Atlas Colon Cancer (TCGA – COAD) Cohort shows up-regulation of COMP correlates with disease stage and molecular subtype and is also associated with poor outcomes" [co-mentor with Dr. Nfonsam].
 
NIH High School Student Research Program: 
Alejandra Montes, Douglas High School (Douglas, AZ), 2020
Sara Schritter, Palo Verde High School, 2020
Sarah Castillo, Flowing Wells High School, 2022
 
Monday, August 31, 2020
Committee Member: 
Committee Vice Chair