Kristian Doyle, PhD

Associate Professor, Immunobiology
Associate Professor, Neurology
Associate Professor, Psychology
Research Scientist
Associate Professor, Neuroscience - GIDP
Associate Professor, BIO5 Institute
Associate Professor, Neurosurgery
 
Education: 
  • University of Sussex, 1996-2000 (BSc)
  • Oregon Health & Science University, 2001-2007 (Ph.D.)
  • Stanford University, 2007-2013 (Postdoctoral Fellowship)
Honors and Awards: 
  • Ellison Medical Foundation Award,  2009 
  • Anita Roberts Young Scientist Award, 2010
  • Undergraduate Biology Research Program (UBRP) Outstanding Faculty Mentor Award, 2016
Selected Publications: 
K.P. Doyle, L.N. Quach, M. Sole, R.C. Axtell, T.V. Nguyen, G.J. Soler-Llavina, S. Jurado, J. Han, L. Steinman, F.M. Longo, J.A. Schneider, R.C. Malenka, M.S. Buckwalter. B-Lymphocyte mediated delayed cognitive impairment following stroke. Journal of Neuroscience, 2015; 35 (5): 2133-2145
 
T.V. Nguyen, J.B. Frye, J.C. Zbesko, K. Stepanovic, M. Hayes, A. Urzua, G. Serrano, T.G. Beach, K.P. Doyle. Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. Acta Neuropathol Commun. 2016 Sep 6; 4 (1):100.
 
K.P. Doyle, M.S. Buckwalter. Does B lymphocyte-mediated autoimmunity contribute to post-stroke dementia? Brain Behavior and Immunity. 2016 Aug 13; 64: 1-8
 
K.P. Doyle. Unraveling the pathophysiology of chronic stroke lesions could yield treatments for stroke-related dementia. Future Neurology, 2016; 11 (1): 1-4
 
J.C. Zbesko, T.V. Nguyen, T. Yang, J. Beischel Frye, O. Hussain, M. Hayes, Amanda Chung, W.A. Day, K. Stepanovic, M. Krumberger, J. Mona, K.P. Doyle. Glial Scars are permeable to neurodegenerative factors present in chronic stroke infarcts. Neurobiology of Disease. 2018 Apr; 112:63-78
 
T.V. Nguyen, M. Hayes, J.B. Frye, J.C. Zbesko, N.P. Belichenko, F. M. Longo, K.P. Doyle. Alzheimer’s disease pathology colocalizes with a homeostatic myelin repair pathway in two mouse models of mixed dementia. Acta Neuropathologica Communications. 2018 Sept; 6 (1):100
 
S. Taylor, E. Mehina, E. White, P. Reeson, K. Doyle, and C. Brown. Suppressing interferon gamma stimulates microglial responses and repair in the diabetic brain. Journal of Neuroscience. 2018 Oct; 38 (40):8707-8722
 
A. Chung, J. Beischel Frye, J.C. Zbesko, E. Constantopoulos, M. Hayes, A.G. Figueroa, W.A. Day, J.P. Konhilas, B.S. McKay, T.V. Nguyen, K.P. Doyle. Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an osteopontin dependent mechanism. eNeuro. 2018 Nov 8;5 (5)
 
NIH Undergraduate Diversity Program: 
Boaz Maiyo, 2021, "Exploring the link between stroke and Alzheimer’s disease"
 
NIH High School Student Research Program: 
Anna Jaison, Bioscience High School (Phoenix, AZ), 2019
 
Wednesday, July 24, 2019
Committee Member: 
Committee Chair