Kellen Chen, PhD

Assistant Research Professor, Surgery and Biomedical Engineering
 
Education: 
  • University of Virginia, 2018 (Ph.D.)
  • University of California, Berkeley, 2013 (B.S.)
Honors and Awards: 
  • Dean Louis J. Kettel Award for exemplary student research mentoring, Medical Student Research Program (MSRP) and Summer Institute on Medical Ignorance (SIMI), 2023
  • Career Development Award, University of Arizona Health Sciences, 2023
  • First Place, University of Arizona Center for Innovation (UACI) Sponsored Launch, 2023
  • First Place, WoundShark Innovation Award, Wound Healing Society, 2023
  • First Place, Young Investigator’s Award, Wound Healing Society, 2022
  • Bernard G. Sarnat, MD, Excellence in Grant Writing Award, Plastic Surgery Foundation, 2021-2022
  • Translational Research Grant, Plastic Surgery Foundation, 2021-2022
  • First Place Basic Science Research Talk, Stanford Plastic Surgery Research Day, 2021
Major Areas of Research Interest: 
  • Therapeutics, fibrosis, wound healing, foreign body response to biomedical implants, mechanotransduction, regeneration, tissue engineering, biomedical engineering therapies to improve outcomes after injury, skin grafting, chronic wound development, biomedical device implantation, and more
Selected Publications: 

Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Disrupting biological sensors of force promotes tissue regeneration in large organisms. Nat Commun.2021 Sep 6;12(1):5256. PMID: 34489407.

Chen K, Henn D, Januszyk M, Barrera JA, Noishiki C, Bonham CA, Griffin M, Tevlin R, Carlomagno T, Shannon T, Fehlmann T, Trotsyuk AA, Padmanabhan J, Sivaraj D, Perrault DP, Zamaleeva AI, Mays CJ, Greco AH, Kwon SH, Leeolou MC, Huskins SL, Steele SR, Fischer KS, Kussie HC, Mittal S, Mermin-Bunnell AM, Diaz Deleon NM, Lavin C, Keller A, Longaker MT, Gurtner GC. Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Sci Transl Med. 2022 May 18;14(645):eabj9152. doi: 10.1126/scitranslmed.abj9152. Epub 2022 May 18. PMID: 35584231.

Chen K, Vigliotti A, Bacca M, McMeeking RM, Deshpande VS, Holmes JW. Role of boundary conditions in determining cell alignment in response to stretch. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):986-991. PMID: 29343646

Chen K, Hu X, Blemker SS, Holmes JW. Multiscale computational model of Achilles tendon wound healing: Untangling the effects of repair and loading. PLoS Comput Biol. 2018 Dec 14;14(12):e1006652. PMID: 30550566

Sponsored Research Through MSRP: 
Ben Litmanovich, (MSRP 2022): "Evaluating the Efficacy of Intravenous Cell Therapy in Accelerating the Diabetic Wound Healing" [co-mentor with Dr. Geoffrey Gurtner]
 
Andrew Hostler, (MSRP 2022): ""
 
NIH Undergraduate Diversity Program: 
Abdel Alsharif, 2023 "Diabetic cellular ecology analysis with ScRNA-seq."
 
NIH High School Student Research Program: 
Brodi Stevens, Central High School (Phoenix, AZ), 2022, 2023
Gabriel Staring, Pueblo High School, 2023
 
Thursday, August 10, 2023