Fayez Ghishan, MD

Department Head, Pediatrics
Professor, Pediatrics
Professor, Physiology
Director, Children's Research Center
Physician-In-Chief, Diamond Children's Medical Center
Professor, Physiological Sciences - GIDP
Honors and Awards: 
  • Chair, Merit Review Committee for Gastroenterology for the Department of Veterans Affairs, 1999
  • North American Society for Pediatric Gastroenterology and Nutrition  Shwachman Award, 2004
Major Areas of Research Interest: 
Molecular characterization of Na+/H+ exchangers and Na/P co-transporter in health and disease states; ontogenic changes in electrolyte transport across the intestinal epithelium to achieve a better understanding of gastrointestinal disorders in early life.
Selected Publications: 
Oweis S. Wu L. Kiela PR. Zhao H. Malhotra D. Ghishan FK. Xie Z. Shapiro JI. Liu J. Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells. American Journal of Physiology - Renal Physiology. 290(5):F997-1008, 2006.

Zawaideh MA. Ghishan FK. Molmenti EP. Regulation of cholesterol homeostasis in solid organ transplantation. Transplantation. 81(3):316-7, 2006.

Ravia JJ. Stephen RM. Ghishan FK. Collins JF. Menkes Copper ATPase (Atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domains. Journal of Biological Chemistry. 280(43):36221-7, 2005.

Kolek OI. Hines ER. Jones MD. LeSueur LK. Lipko MA. Kiela PR. Collins JF. Haussler MR. Ghishan FK. 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(6):G1036-42, 2005.

Xu H. Chen R. Ghishan FK. Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(1):G36-41, 2005.
Sponsored Research Through MSRP: 
Creed Rucker (MSRP 1997):  "Expression of sodium/hydrogen exchanger isoforms in the diabetic rat."
Nouralhoda Dehdashti (MSRP 2013): "Extra Intestinal Manifestations of Colitis Induced Mice."
Advanced Research Distinction Track (RDT): 
Nouralhoda Dehdashti (RDT Class of 2014): "Cav1.3 Calcium Channel Expression in Inflammatory Bowel Disease" 
NIH High School Student Research Program: 
Leann  Verdugo, Catalina High School, 1995, 1996, 1997, 1998
Vincent Korta (Steele Memorial Fellow) , Dobson High School (Phoenix, AZ), 1999
Annie Maiden  (Steele Memorial Fellow), Central High School, 2000
Andrea Caballero Canez, Cholla High Magnet School, 2011
Monday, March 5, 2018