Elizabeth Connick, MD

Professor, Medicine
Division Chief, Infectious Disease

Professor, Immunobiology

Professor, BIO5 Institute

Education:

Harvard Medical School, Boston (M.D.)
Columbia University, New York (Post-Grad)
Bryn Mawr College, Bryn Mawr, Pa. (A.B., Anthropology)

Major Areas of Research Interest:

Dr. Connick’s research, much of it funded by the National Institutes of Health (NIH), targets HIV immunopathogenesis — disease development involving an immune response or a related component. She has been involved in clinical trials as well as laboratory-based translational research studies of HIV-1 infection for more than 20 years, including studies of acute HIV infection, immune reconstitution, cardiovascular disease and HIV pathogenesis among women. More recently, she has focused on strategies to develop a cure for HIV infection. Throughout her career, Dr. Connick has received research funding totaling nearly $14.2 million as principal investigator, $43.5 million as co-investigator and $121.5 million in other roles.

Selected Publications:

Kohler, S. L., Pham, M. N., Folkvord, J. M., Arends, T., Miller, S. M., Miles, B., Meditz, A. L., McCarter, M., Levy, D. N., & Connick, E. (2016). Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication. Journal of immunology (Baltimore, Md. : 1950), 196(6), 2711-22.

Li, S., Folkvord, J. M., Rakasz, E. G., Abdelaal, H. M., Wagstaff, R. K., Kovacs, K. J., Kim, H. O., Sawahata, R., MaWhinney, S., Masopust, D., Connick, E., & Skinner, P. J. (2016). Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo. Journal of virology, 90(24), 11168-11180.

Miles, B., & Connick, E. (2016). TFH in HIV Latency and as Sources of Replication-Competent Virus. Trends in microbiology, 24(5), 338-44.

Miles, B., Miller, S. M., Folkvord, J. M., Levy, D. N., Rakasz, E. G., Skinner, P. J., & Connick, E. (2016). Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection. PLoS pathogens, 12(10), e1005924.

Miles, B., Miller, S., & Connick, E. (2016). CD4 T Follicular Helper and Regulatory Cell Dynamics and Function in HIV Infection. Frontiers in Immunology, https://doi.org/10.3389/fimmu.2016.00659. doi:https://doi.org/10.3389/f...

Haas, M. K., Levy, D. N., Folkvord, J. M., & Connick, E. (2015). Distinct patterns of Bcl-2 expression occur in R5- and X4-tropic HIV-1-producing lymphoid tissue cells infected ex vivo. AIDS research and human retroviruses, 31(3), 298-304.

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