Professor, Pathology
Professor, Applied BioSciences
Associate Professor, BIO5 Institute
Professor, Applied BioSciences
Associate Professor, BIO5 Institute
Education:
- Karl Ruprecht University of Heidelberg, 1982 (M.S., Biology)
- German Cancer Research Center,1989 (Ph.D., Cell & Tumor Biology)
Research Activities:
- Mechanism of Lymphoma
Selected Publications:
2017
Kendrick S, Rimsza LM, Scott DW, Slack GW, Farinha P, Tan KL, Persky D, Puvvada S, Connors JM, Sehn L, Gascoyne RD, Schmelz M. Aberrant cytoplasmic expression of MHCII confers worse progression free survival in diffuse large B-cell lymphoma. Virchows Archiv, 2017, Vol 470 (1), 113-117. (DOI: 10.1007/s00428-016-2041-7; PMID: 27888357). http://link.springer.com/article/10.1007/s00428-016-2041-7
2016
Puvvada SD, Li H, Rimsza LM, Bernstein SH, Fisher RI, LeBlanc M, Schmelz M, Glinsmann-Gibson B, Miller TP, Maddox AM, Friedberg JW, Smith SM, Persky DO. A phase II study of belinostat (PXD101) in relapsed and refractory aggressive B-cell lymphomas: SWOG S0520. See comment in PubMed Commons belowLeukemia & Lymphoma, 2016 Jan 12:1-11. [Epub ahead of print].
Redd L, Schmelz M, Burack R, Cook JR, Day AW, Rimsza LM. Langerhans Cell Histiocytosis (LCH) shows distinct cytoplasmic expression of the major histocompatibility class II antigen (MHCII) in LCH. J. Hematopathology, 2016, 9: 107-112. DOI 10.1007/s12308-016-0272-9. (http://link.springer.com/search?sortOrder=newestFirst&facet-content-type=Article&facet-journal-id=12308).
Havas AB, Rodrigues KB, Bhakta A, Demirjian JA, Hahn S, Tran J, Scavello M, Tula-Sanchez AA, Zeng Y, Schmelz M, Smith CL. Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma. Cancer Biology & Therapy 2016, Vol 0, No. 0, 1-13. (http://dx.doi.org/10.1080/15384047.2016.1250046).
2012
Schmelz M, Montes-Moreno S, Piris MA, Wilkinson ST, Rimsza LM. Lack and/or aberrant localization of major histocompatibility Class II (MHCII) protein in plasmablastic lymphoma. Haematologica 97(10):1614-6; 2012.
2010
Jensen, V., A. R. Prasad, A. Smith, M. Raju, C. S. Wendel, M. Schmelz, W. Leyva, J. Warneke, and R. S. Krouse, "Prognostic criteria for squamous cell cancer of the skin.", J Surg Res, vol. 159, issue 1, pp. 509-16, 2010 Mar. PMID: 19375720
2009
Thai, H. M., E. Juneman, J. Lancaster, T. Hagerty, R. Do, L. Castellano, R. Kellar, S. Williams, G. Sethi, M. Schmelz, et al., "Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction.", Cell Transplant, vol. 18, issue 3, pp. 283-95, 2009. PMCID: PMC2739416 PMID: 19558777
2007
Li, L., M. Schmelz, E. M. Kellner, J. N. Galgiani, and M. J. Orbach, "Nuclear labeling of Coccidioides posadasii with green fluorescent protein.", Ann N Y Acad Sci, vol. 1111, pp. 198-207, 2007 Sep. PMID: 17344520
2006
Kremer, C. L., M. Schmelz, and A. E. Cress, "Integrin-dependent amplification of the G2 arrest induced by ionizing radiation.", Prostate, vol. 66, issue 1, pp. 88-96, 2006 Jan 1. PMCID: PMC2732347 PMID: 16114062
2005
Li, L., S. M. Dial, M. Schmelz, M. A. Rennels, and N. M. Ampel, "Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis.", Infect Immun, vol. 73, issue 7, pp. 3923-8, 2005 Jul. PMCID: PMC1168614 PMID: 15972478
Sponsored Research Through MSRP:
Julia Freeman, (MSRP 2017): "MHC II Trafficking in Lymphoma (DLBCL) and its Impact on MHC II Expression"
April Olson, (MSRP 2018): "Determining Phenotypes of Lymphoma Cell Lines by CD30 Expression."
NIH High School Student Research Program:
Frances Esparza, 2001, Cholla High School
Jaylene Arvizu, 2015, Nogales High School
Agustin Contreras, 2016, San Luis High School
Thursday, August 9, 2018