Elizabeth Juneman, MD, FACC

Affiliate - Associate Professor of Medicine
 
Education: 
  • Southern Methodist University, Dallas, Texas, 1992-1996  (B.S., Electrical Engineering)
  • University of Texas – Houston 1996-2000 (M.D.)
  • University of Arizona, 7/2000-6/2001 (Internship in Internal Medicine)
  • University of Arizona,  7/2001-6/2003 (Residency in Internal Medicine)
  • University of Arizona, 7/2003-6/2004 (Chief Resident in Internal Medicine) 
  • University of Arizona, 7/2004-6/2006 (Fellowship in Cardiology) 
  • University of Arizona, 7/2006-6/2007 (Chief Fellow in Cardiology)
Honors and Awards: 
  • Tau Beta Pi National Engineering Honor Society, Texas Iota Chapter Southern Methodist University 1995
  • Eta Kappa Nu Electrical Engineering Honor Society, Southern Methodist University 1995
  • Susan M. Allen Award for Outstanding Intern of the Year, Department of Medicine University of Arizona 2001
  • ACP-ASIM Annual Vignette Competition Winner, Department of Medicine University of Arizona 2002
  • Charles W. Hall, Jr. Memorial Award for Outstanding Cardiac Care Unit Resident Department of Cardiology, University of Arizona 2002
  • Astra Zeneca Scholars Award Winner, American Federation for Medical Research – Western Section 2003
  • Novartis Cardiovascular/Renal Scholars Award Winner, American Federation for Medical Research -- Western Section 2004
  • Cardiovascular Scholar Awards Winner, American Federation for Medical Research -- Western Section 2006
  • Special Recognition Award, Southern Arizona VA Health Care System 2009
  • Finalist, Basic Science Junior Faculty, Northwestern Cardiovascular Young Investigators’ Forum 2009
  • Second Place Finalist and Scholarship Winner, Basic Science Junior Faculty, Northwestern Cardiovascular Young Investigators’ Forum 2010
  • Tucson’s Best Doctors, Cardiology, Tucson Lifestyle 2009-2014
  • The Charles W. Hall Jr. Memorial Cardiology Fellowship Teaching Award, Sarver Heart Center, University of Arizona 2011
  • Finalist, Basic Science Junior Faculty, Northwestern Cardiovascular Young Investigators’ Forum 2011
  • Physician of the Year, Southern Arizona VA Health Care System 2013
Research Activities: 
Research Work In-Process:
  • Biologically Active Cardiomyocyte Patch: Inject inducible pluripotent stem cells into a fibroblast seeded patch to study in-vitro the cellular interactions. 
  • Cell-Based Therapy on Diastolic Function in Heart Failure: Aimed to determine if cell-based therapy in CHF improves in LV diastolic function by reducing mechanical restraint.
  • Cardiac Electrical Mapping with Advanced Electrode Array and Ultrasound Techniques.
  • Validation of Merck HDAC inhibitor, MK-3336, on Cardiac Structure and Function in the Rat MI Heart Failure Model.
Selected Publications: 
Peer Reviewed Published:
Shinde AA, Juneman EB, Mitchell B, Pierce MK, Gaballa M, Goldman S, Thai HM.  Shocks from Pacemaker Cardioverter Defibrillator Increase with Amiodarone in Patients at High Risk for Sudden Cardiac Death.  Cardiology 2003; 100:143-148. PMID: 14631135
 
Thai HM, Juneman EB, Castellano L, Phan H, Do R, Johnson N, Gaballa M, Goldman S. Pretreatment With Angiotensin Receptor Blockade Prevents Left Ventricular Dysfunction and Blunts Left Ventricular Remodeling Associated With Acute Myocardial Infarction.  Circulation 2006; 114:1933-1939. PMID: 17060375
 
Rough S, Juneman E, Fain M. Aldosterone Receptor Antagonists Therapy in Older Heart Failure Patients: Another Look. Arizona Geriatric Society Journal 2007;12(2):10-13.
 
S Thal, H Thai, E Juneman, S Goldman.  Coronary Sinus Diverticulum Complicating CRT Device Implantation.  PACE 2008; 31:1184-1185. PMID: 18834471
 
H Thai, E Juneman, J Lancaster, T Hagerty, R Do, L Castellano, R Kellar, S Williams, G Sethi, M Schmelz, M Gaballa, S Goldman.  Implantation of a Three-Dimensional Fibroblast Matrix Improves Left Ventricular Function and Blood Flow After Acute Myocardial Infarction. Cell Transplantation 2009; 18(3):283-295. PMID: 19558777
 
Lancaster J, Juneman E, Hagerty T, Do R, Hicks M, Meltzer K, Standley P, Gaballa M, Kellar R, Goldman S, Thai H.  Viable fibroblast matrix patch induces angiogenesis and increases myocardial blood flow in heart failure after myocardial infarction. Tissue Engineering 2010; 16(10):3065-3073. PMID: 20486785
 
Kellar R, Lancaster J, Hoang T, Juneman E, Johnson N, Byrne H, Stansifer M, Bebbington C, Yarranton G, Goldman S. Antibody to Granulocyte Macrophage Colony–stimulating Factor Reduces the Number of Activated Tissue Macrophages and Improves Left Ventricular Function After Myocardial Infarction in a Rat Coronary Artery Ligation Mode. Journal of Cardiovascular Pharmacology 2011; 57:568–574. PMID: 21326109
 
Saleh L, Juneman E, Movahed R. The use of gadolinium in patients with contrast allergy or renal failure requiring coronary angiography, coronary intervention, or vascular procedure. Catheterization and Cardiovascular         Interventions 2011; Nov 1;78(5):747-54. PMID: 21780275
 
Goldman S, Sethi GK, Holman W, Thai H, McFalls E, Ward HB, Kelly RF, Rhenman B, Tobler GH, Bakaeen FG, Huh J, Soltero E, Moursi M, Haime M, Crittenden M, Kasirajan V, Ratliff M, Pett S, Irimpen A, Gunnar W, Thomas D, Fremes S, Moritz T, Reda D, Harrison L, Wagner TH, Wang Y, Planting L, Miller M, Rodriguez Y, Juneman E, Morrison D, Pierce MK, Kreamer S, Shih MC, Lee K.  Radial Artery vs. Saphenous Vein Grafts in Coronary Artery Bypass Surgery: A Randomized Trial. JAMA 2011; 305(2):167-174. PMID: 21224458
 
Kowey PR, Crijns HJ, Aliot EM, Capucci A, Kulakowski P, Radzik D, Roy D, Connolly SJ, Hohnloser SH; ALPHEE Study Investigators. Efficacy and safety of celivarone, with amiodarone as calibrator, in patients with an implantable cardioverter-defibrillator for prevention of implantable cardioverter-defibrillator interventions or death: the ALPHEE study. Circulation 2011 Dec 13;124(24):2649-60. PMID: 22082672
 
S Thal, R Boyella, R Arsanjani, E Juneman, R Movahed, H Thai, S Goldman. Unusual Combination of Holt-Oram Syndrome and Persistent Left Superior Vena Cava. Congenital Heart Disease 2012; Jul-Aug;7(4):E46-9. PMID: 22129221
 
Juneman EB, Saleh L, Lancaster JJ, Thai HM, Markham B, Goldman S. The effects of poloxamer-188 on left ventricular function in chronic heart failure after myocardial infarction. J Cardiovasc Pharmacol. 2012 Sep;60(3):293-8. PMID: 22653419
 
Bakaeen FG, Sethi G, Wagner TH, Kelly R, Lee K, Upadhyay A, Thai H, Juneman E, Goldman S, Holman WL. Coronary artery bypass graft patency: residents versus attending surgeons. Ann Thorac Surg. 2012 Aug;94(2):482-8; discussion 488. PMID: 22698772
 
Farkouh ME, Domanski M, Sleeper LA, Siami FS, Dangas G, Mack M, Yang M, Cohen DJ, Rosenberg Y, Solomon SD, Desai AS, Gersh BJ, Magnuson EA, Lansky A, Boineau R, Weinberger J, Ramanathan K, Sousa JE, Rankin J, Bhargava B, Buse J, Hueb W, Smith CR, Muratov V, Bansilal S, King S 3rd, Bertrand M, Fuster V; FREEDOM Trial Investigators. Strategies for multivessel revascularization in patients with diabetes. N Engl J Med. 2012 Dec 20;367(25):2375-84. PMID: 23121323
 
Juneman E, Saleh L, Thai H, Goldman S, Movahed MR. Successful coronary angiography with adequate image acquisition using a combination of gadolinium and a power injector in a patient with severe iodine contrast allergy. Exp Clin Cardiol. 2012 Winter;17(1):17-9. PMID: 23204895
 
Gheorghiade M, Böhm M, Greene S, Fonarow G, Lewis E, Zannad F, Solomon S, Baschiera F, Botha J,  Hua T,  Gimpelewicz C, Jaumont X,  Lesogor A, Maggioni A; for the ASTRONAUT Investigators and Coordinators. Effect of Aliskiren on Postdischarge Mortality and Heart Failure Readmissions Among Patients Hospitalized for Heart Failure: The ASTRONAUT Randomized Trial. JAMA. 2013; 309 (11): 1125-1135.
 
Nguyen J, Juneman E, Movahed MR. The Value of β-Blockers Administration during Recovery Phase of Dobutamine Stress Echocardiography: A Review. Echocardiography. 2013 Apr 8. PMID: 23560565
 
Tanaka DT, Lancaster JJ, Juneman E, Bahl J, and Goldman S.  Clenbuterol Plus Granulocyte Colony-Stimulating Factor Regulates Stem/Progenitor Cell Mobilization and Exerts Beneficial Effects by Increasing Neovascularization in Rats with Heart Failure.  Journal of Cardiac Failure.  2013; 19(7):503-508.
 
Juneman E, Arsanjani R, Thai H, Lancaster J, Madwed J, Goldman S. Development of a Novel Sodium-Hydrogen Exchanger Inhibitor for Heart Failure.  Journal of Cardiology and Vascular Medicine.  2013; 1 (1).
 
Maggioni AP, Greene SJ, Fonarow GC, Böhm M, Zannad F, Solomon SD, Lewis EF, Baschiera F, Hua TA, Gimpelewicz CR, Lesogor A, Gheorghiade M; ASTRONAUT Investigators and Coordinators. Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial. Eur Heart J. 2013 Oct;34(40):3117-27.
 
Lancaster JJ, Arnce SA, Johnson NM, Juneman E, Thai H, Kellar R, Vitorin JE, Burt J, Gaballa MA, Bahl JJ, Goldman S.  An electrically coupled tissue-engineered cardiomyocyte scaffold improves cardiac function in rats with chronic heart failure.  Journal of Heart and Lung Transplantation 2014 Apr; 33(4):438-45. 
 
Khan MF, Gottesman S, Boyella R, Juneman E. Gemcitabine-induced cardiomyopathy: a case report and review of the literature. J Med Case Rep. 2014 Jun 23;8:220. 
 
Current Manuscripts in Progress: 
E Juneman, T Troung, L Saleh, T Hagerty, J Lancaster, H Thai, S Goldman. Hypothermia normalizes LV hemodynamic parameters, prevents LV dysfunction and restores LV remodeling in acute myocardial infarction.  (In preparation for submission.) 
 
E Juneman, P Suryanarayana, J Lancaster, S Goldman. Aliskiren in Ischemic Heart Failure and Left Ventricular Remodeling. (In preparation for submission).
 
Hernandez C, K Reed, E Juneman, W Cohen. Changes in Sonographically Measured Inferior Vena Cave Diameter in Response to Fluid Loading in Term Pregnancy. (Submitted American Journal of Obstetrics and Gynecology, 2015).
 
Pandey A, Juneman E, Jahardanan R, Thal S. Complications of Pacer Implantation in Patient with Left Persistent Super Vena Cava. (In preparation for submission).
 
Pandey A, Lancaster J, Goldman S, Juneman E. Mesenchymal Stem Cells Use in Heart Failure: An Update. (Submitted, 2015).
 
Sanchez P, Lancaster J, Weigand K, Goldman S, Juneman E. Diastolic tissue Doppler reflects the severity of injury in rats with chronic heart failure. (In preparation for submission).
 
Book Chapters:
“Non-Cardiac Findings on Echocardiography” chapter, Author: E Juneman. Questions, Tips and Tricks for the Echocardiography Boards. Editors: Vincent L. Sorrell and Sasanka Jayasuria. Lippincott, Williams & Wilkins, 2014.
 
Research Work In-Process:
Biologically Active Cardiomyocyte Patch: Inject inducible pluripotent stem cells into a fibroblast seeded patch to study in-vitro the cellular interactions.
 
Cell-Based Therapy on Diastolic Function in Heart Failure: Aimed to determine if cell-based therapy in CHF improves in LV diastolic function by reducing mechanical restraint.
 
Cardiac Electrical Mapping with Advanced Electrode Array and Ultrasound Techniques.
 
Validation of Merck HDAC inhibitor, MK-3336, on Cardiac Structure and Function in the Rat MI Heart Failure Model.
 
Sponsored Research Through MSRP: 
Nicole LaHood, (MSRP 2012): "Electrical Coupling of a Biological Active Cardiomyocyte Patch"
 
Rose Sivilli, (MSRP 2014): "Using Cardiac Ultrasound to Assess the Diastolic Function of the Left Ventricle in a Post-Coronary Artery Ligation Rat Model"
 
Giuliana Repetti, (MSRP 2016): "Tagging and Characterization of iPS-Derived Cardiomyocytes Implanted into a Rat Model of Chronic Heart Failure"
 
Satnam Khalsa, (MSRP 2017): "Immune Response to Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Graft for the Treatment of Heart Failure in a Rat Model"
 
Craig Morris, (MSRP 2017, 2020): "Electrophysiological Characterization of Cardiomyopathies in Knock-Out Murine Mice"
 
Advanced Research Distinction Track (RDT): 
Nicole LaHood, (RDT Class of 2015): "Development of Electrophysiologic Cardiac Mapping Modalities in Small Animals"
 
Giuliana Repetti, (RDT Class of 2019): "Mechanisms of an iPSC-Derived Cardiac Graft to Treat Heart Failure"
 
Satnam Khalsa, (RDT Class of 2020): "Immune Response to Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Graft for the Treatment of Heart Failure in a Rat Model"
 
Craig Morris, (RDT Class of 2020): "Electrophysiological Characterization of Cardiomyopathies in Knock-Out Murine Mice"
 
Ikeotunye Chinyere (RDT Class of 2023): "Effective Refractory Period and Ventricular Tachycardia in Heart Failure with Reduced Ejection Fraction"
 
NIH Undergraduate Diversity Program: 
Reginald Myles II, 2017; "A Look Into Niemann Pick C1"
 
Tuesday, August 29, 2017