Ronald L. Heimark, PhD

Chief, Section of Surgical Research
Professor, Surgery
Professor,
Pathology
Professor, Cell Biology and Anatomy

Education: 
  • Western Washington State University, 1970 (B.A.)
  • University of California, Davis, 1976 (Ph.D.)
Honors and Awards: 
  • Irvine H. Page Research Award for Young Investigators, 1984
Major Areas of Research Interest: 
  • Molecular mechanisms of angiogenesis and prostate carcinoma epithelial-mesenchymal transformation
  • Regulation of cadherins in vascular morphogenesis
Sponsored Research Through MSRP: 

Chandra Krishan (MSRP 2001): "Outside-in signalling by N-cadherin in vascular remodeling."

Venkatesh Anjan (MSRP 2005): "The role of ZBP89 in prostate carcinoma metastasis."

Luis Camacho (MSRP 2016): "Role of miR-302-367 Cluster in Pancreatic Ductal Adenocarcinoma."

Selected Publications: 

Cox CM, D'Agostino SL, Miller MK, Heimark RL, Krieg PA. Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo. Dev Biol. 2006 (E-publication).

Alexander NR, Tran NL, Rekapally H, Summers CE, Glackin C, Heimark RL. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Res. 66(7):3365-9, 2006.

Derbyshire ZE, Halfter UM, Heimark RL, Sy TH, Vaillancourt RR. Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II. Mol Cell Biochem. 271(1-2):77-90, 2005.

Vokes SA, Yatskievych TA, Heimark RL, McMahon J, McMahon AP, Antin PB, Krieg PA. Hedgehog signaling is essential for endothelial tube formation during asculogenesis. Development. 131(17):4371-80, 2004.

NIH Undergraduate Diversity Program: 

 Diana Pham, 2015; "Regeneration of the Pancreas After Acute Inflammation"

NIH High School Student Research Program: 

- Amanda V. Valles, Amphitheater High School, 2001
-Philip Sandoval, Morenci High School, 2003

NIH K-12 Science Teacher Program: 

-Stephen A. Ahmann, Morenci High School, 2001
-Brad Donaldson, Buena High School, 2003

Monday, May 22, 2017