Department Head, Pediatrics
Professor, Pediatrics
Professor, Physiology
Director, Children's Research Center
Physician-In-Chief, Diamond Children's Medical Center
Professor, Pediatrics
Professor, Physiology
Director, Children's Research Center
Physician-In-Chief, Diamond Children's Medical Center
Professor, Physiological Sciences - GIDP
Honors and Awards:
- Chair, Merit Review Committee for Gastroenterology for the Department of Veterans Affairs, 1999
- North American Society for Pediatric Gastroenterology and Nutrition Shwachman Award, 2004
Major Areas of Research Interest:
Molecular characterization of Na+/H+ exchangers and Na/P co-transporter in health and disease states; ontogenic changes in electrolyte transport across the intestinal epithelium to achieve a better understanding of gastrointestinal disorders in early life.
Selected Publications:
Oweis S. Wu L. Kiela PR. Zhao H. Malhotra D. Ghishan FK. Xie Z. Shapiro JI. Liu J. Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells. American Journal of Physiology - Renal Physiology. 290(5):F997-1008, 2006.
Zawaideh MA. Ghishan FK. Molmenti EP. Regulation of cholesterol homeostasis in solid organ transplantation. Transplantation. 81(3):316-7, 2006.
Ravia JJ. Stephen RM. Ghishan FK. Collins JF. Menkes Copper ATPase (Atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domains. Journal of Biological Chemistry. 280(43):36221-7, 2005.
Kolek OI. Hines ER. Jones MD. LeSueur LK. Lipko MA. Kiela PR. Collins JF. Haussler MR. Ghishan FK. 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(6):G1036-42, 2005.
Xu H. Chen R. Ghishan FK. Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(1):G36-41, 2005.
Zawaideh MA. Ghishan FK. Molmenti EP. Regulation of cholesterol homeostasis in solid organ transplantation. Transplantation. 81(3):316-7, 2006.
Ravia JJ. Stephen RM. Ghishan FK. Collins JF. Menkes Copper ATPase (Atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domains. Journal of Biological Chemistry. 280(43):36221-7, 2005.
Kolek OI. Hines ER. Jones MD. LeSueur LK. Lipko MA. Kiela PR. Collins JF. Haussler MR. Ghishan FK. 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(6):G1036-42, 2005.
Xu H. Chen R. Ghishan FK. Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8. American Journal of Physiology - Gastrointestinal & Liver Physiology. 289(1):G36-41, 2005.
Sponsored Research Through MSRP:
Creed Rucker, (MSRP 1997): "Expression of sodium/hydrogen exchanger isoforms in the diabetic rat."
Nouralhoda Dehdashti, (MSRP 2013): "Extra Intestinal Manifestations of Colitis Induced Mice."
Advanced Research Distinction Track (RDT):
Nouralhoda Dehdashti, (RDT Class of 2014): "Cav1.3 Calcium Channel Expression in Inflammatory Bowel Disease"
NIH High School Student Research Program:
Leann Verdugo, Catalina High School, 1995, 1996, 1997, 1998
Vincent Korta (Steele Memorial Fellow) , Dobson High School (Phoenix, AZ), 1999
Annie Maiden (Steele Memorial Fellow), Central High School, 2000
Andrea Caballero Canez, Cholla High Magnet School, 2011
Alani Martinez, Kofa High School (Yuma, AZ), 2020
Monday, March 5, 2018