Edward D. French, PhD

Professor, Pharmacology
College of Medicine
Additional Contact Info: 

Fax: (520) 626-2204

Education: 
  • University of California at Los Angeles, 1976, Pharmacology (Ph.D.)
  • A.V. Davis Center for Behavioral Neurobiology, The Salk Institute, La Jolla, 1976-1979 (Post-doctoral Fellow)
  • Max-Planck Institute for Psychiatry, Munich, Federal Republic of Germany, 1979-1980 (Alexander von Humboldt Fellow)
Honors and Awards: 

National Research Service Award, National Institute for Mental Health

Alexander von Humboldt Fellowship, Humboldt Foundation, Federal Republic of Germany
Faculty Teaching Award, University of Arizona, 2003

Major Areas of Research Interest: 

As a neuropharmacologist, my research has focused on the central sites and mechanisms of actions of drugs of abuse. Our investigations are aimed at trying to unravel the neurobiological consequences attendant to acute and chronic drug exposure, and to use these same drugs as tools to better understand basic central nervous system processes. Our research which is conducted in experimental animals is aimed at:

1. Identifying the mechanism of action of phencyclidine (PCP), nicotine and delta-9-tetrahydrocannabinol (marijuana) on those dopamine neurons projecting to limbic and cortical areas of the brain.

2. Characterizing the ionic mechanisms by which these drugs affect the activity of central neurons using voltage-clamp electrophysiological techniques.

3. Developing an animal model of drug self-administration that can be used to test hypotheses concerning the neurobiology of schizophrenia.

Sponsored Research Through MSRP: 

Dianna Williams (MSRP 1992, 1993): "Evaluation of the effects of serotonin in a self administering model of phencyclidine abuse."

Wednesday, November 18, 2015