Patricia B. Hoyer, PhD

Professor, Physiology

Adjunct Professor, Animal Science

Investigator, Center for Toxicology

Professor, Pharmacology & Toxicology

Department of Physiology

AHSC 4122; P.O. Box 245051

Tucson, AZ 85724-5051

(520) 626-6688
Email Address:
  • University of Wyoming, 1981 (PhD, Biochemistry)
  • Colorado State University, 1984 (Postdoctoral, Physiology & Biophysics)
Honors & Awards: 
  • President- Mountain West Society of Toxicology (1999-2000)
  • Editorial Board- Biology of Reproduction (1995-1999; 2001-2004)
  • Associate Editor- Toxicology and Applied Pharmacology (2001-2003)
  • Founders' Day Award- College of Medicine, University of Arizona (2002)
  • Editorial Board- Reproduction and Developmental Toxicology Journal (2003-present)
  • Board of Directors- Society for Study of Reproduction (2003-2006)
Major Areas of Research Interest: 
  • Elucidating signaling pathways that regulate cell death by apoptosis
  • Establishing mechanisms of ovotoxicity caused by environmental chemicals
  • Developing models that alter the rate of atresia in ovarian follicles
  • Understanding mechanisms that regulate regression in the corpus luteum
Selected Publications: 

Lohff JC, Christian PJ, Marion SL, Hoyer PB. Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause. Menopause. 2006 (E-publication).

Flaws JA, Marion SL, Miller KP, Christian PJ, Babus JK, Hoyer PB. Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-binylcyclohexene. Toxicol Appl Pharmacol. 2006 (E-publication).

Lohff JF, Christian PJ, Marion SL, Arrandale A, Hoyer PB. Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause. Comp Med. 55(6):523-7, 2005.

Mayer LP, Dyer CA, Eastgard RL, Hoyer PB, Banka CL. Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause. Arterioscler Thromb Vasc Biol. 25(9):1910-6, 2005.

Hoyer PB. Damage to ovarian development and function. Cell Tissue Res. 322(1):99-106, 2005.

Student Opportunities Through Research: 
  • Learn radioimmunoassay
  • Assist with sheep surgery
  • Learn rat vaginal smearing
NIH High School Student Research Program: 

-Jilian Hien Pham, Santa Rita High School, 1991

-Falgunee Parekh, Thunderbird High School (Phoenix), 1992

-James Scott Kanter, Sabino High School, 1993

-Beatrice James, Monument Valley High School, 1998

-Nathan Tafoya, University High School, 1999

-Negin Nematollahi, Tucson High Magnet School, 2008

Last Updated: 
November 18, 2015